Application | Comment | Organism |
---|---|---|
medicine | inhibitors CEL5-A, CEL5-G, EA-1, block production of known precursors to neurofibrillary tangles in hippocampal slices, link of enzyme lysosomal disfunction to the etiology of Alzheimers disease | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CEL5-A | disruption of single- to heavy-chain formation | Rattus norvegicus | |
CEL5-G | disruption of single- to heavy-chain formation | Rattus norvegicus | |
EA-1 | disruption of single- to heavy-chain formation | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | hippocampal slice cultures | Rattus norvegicus | - |