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Literature summary for 3.4.23.5 extracted from
- Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis (2003), J. Biol. Chem., 278, 31401-31411.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | inhibition of enzyme by pepstatin A inhibits early apoptotic events and delays cell death in T lymphocytes exposed to apoptotic stimuli targeting mitochondria | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| pepstatin A | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| T lymphocyte | - |
Homo sapiens | - |
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