Any feedback?
Literature summary for 3.4.23.5 extracted from
- A replacement of the active-site aspartic acid residue 293 in mouse cathepsin D affects its intracellular stability, processing and transport in HEK-293 cells (2003), Biochem. J., 369, 55-62.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D293N | complete loss of activity, enzyme is unstable and proteolytically modified during early steps of secretory pathway resulting in loss of mass by 1 kDa, enzyme transport to the lysosome is delayed | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
