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Literature summary for 3.4.23.5 extracted from
- Purification and characterization of a digestive cathepsin D proteinase isolated from Tribolium castaneum larvae (Herbst) (1996), Insect Biochem. Mol. Biol., 26, 95-100.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Monoiodoacetic acid | - |
Tribolium castaneum |  |
| pepstatin | pepstatin A | Tribolium castaneum | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 22000 | - |
x * 22000, SDS-PAGE | Tribolium castaneum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Tribolium castaneum | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| no modification | enzyme contains no carbohydrate | Tribolium castaneum |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Tribolium castaneum |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| larva | - |
Tribolium castaneum | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Tribolium castaneum |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -80°C, stable | Tribolium castaneum |
| 4°C, complete loss of activity after 72 h | Tribolium castaneum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Albumin + H2O | no activity with bovine serum albumin | Tribolium castaneum | ? | - |
? | |
| Hemoglobin + H2O | - |
Tribolium castaneum | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 22000, SDS-PAGE | Tribolium castaneum |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 4 | - |
72 h, complete loss of activity | Tribolium castaneum |
| 55 | - |
15 min, more than 50% loss of activity | Tribolium castaneum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 3 | - |
- |
Tribolium castaneum |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 2 | 3.5 | about 65% of maximal activity at pH 2.0 and at pH 3.5 | Tribolium castaneum |
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Release 2023.1 (January 2023)
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