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Literature summary for 3.4.23.5 extracted from

  • Figueiredo, A.F.S.; Takii, Y.; Tsuji, H.; Kato, K.; Inagami, T.
    Rat kidney renin and cathepsin D: purification and comparison of properties (1983), Biochemistry, 22, 5476-5481.
    View publication on PubMed
Search for more literature for 3.4.23.5

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40740
-
 Cath D-I and Cath D-III, gel filtration Rattus norvegicus
42660
-
 Cath D-II, gel filtration Rattus norvegicus
45000
-
 1 * 45000, Cath D-II SDS-PAGE Rattus norvegicus
46000
-
 1 * 46000, Cath D-I and Cath D-III, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
3 cathepsin D components: Cath-D-I, Cath D-II, and Cath D-III Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus

Storage Stability

Storage Stability Organism
4°C, pH 7, stable for at least 4 months Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Hemoglobin + H2O
-
 Rattus norvegicus ?
-
 ?
additional information enzyme catalyzes angiotensin I generation Rattus norvegicus ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 45000, Cath D-II SDS-PAGE Rattus norvegicus
monomer 1 * 46000, Cath D-I and Cath D-III, SDS-PAGE Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
3
-
 2 optima: pH 3.0 and pH 4.5, hydrolysis of hemoglobin Rattus norvegicus
4.5
-
 2 optima: pH 3.0 and pH 4.5, hydrolysis of hemoglobin Rattus norvegicus