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Literature summary for 3.4.23.49 extracted from

  • Brandenburg, K.; Garidel, P.; Schromm, A.B.; Andra, J.; Kramer, A.; Egmond, M.; Wiese, A.
    Investigation into the interaction of the bacterial protease OmpT with outer membrane lipids and biological activity of OmpT:lipopolysaccharide complexes (2005), Eur. Biophys. J., 34, 28-41.
    View publication on PubMed
Search for more literature for 3.4.23.49

Activating Compound

Activating Compound Comment Organism Structure
lipopolysaccharides e.g. LPS K12, required for activity, lipid-protein interactions, complex activity analysis on model membranes and human mononuclear cells, overview Escherichia coli
Phospholipids lipid-protein interactions Escherichia coli

Cloned(Commentary)

Cloned (Comment) Organism
recombinant expression of OmpT in inclusion bodies Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
outer membrane enzyme incorporation mechanism into membranes, overview Escherichia coli 19867
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli the enzyme is involved in cell defense and induced production of TNFalpha, especially in clinical isolates, the enzyme is not stimulated by toll-like receptors 2 and 4 signalling ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 enzyme-LPS activity in endotoxin units Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in cell defense and induced production of TNFalpha, especially in clinical isolates, the enzyme is not stimulated by toll-like receptors 2 and 4 signalling Escherichia coli ?
-
 ?
additional information protein-lipid interactions on model membranes and human mononuclear cells, overview Escherichia coli ?
-
 ?

Subunits

Subunits Comment Organism
More enzyme secondary structure analysis Escherichia coli

Synonyms

Synonyms Comment Organism
ompT
-
 Escherichia coli