Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
YapE + H2O | Yersinia pestis | Yersinia pestis autotransporter YapE protein | ? | cleavage of YapE occurs in Yersinia pestis but not in the enteric Yersinia species, and requires the omptin Pla | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Yersinia pestis | P17811 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
YapE + H2O | Yersinia pestis autotransporter YapE protein | Yersinia pestis | ? | cleavage of YapE occurs in Yersinia pestis but not in the enteric Yersinia species, and requires the omptin Pla | ? |
Synonyms | Comment | Organism |
---|---|---|
YapE | - |
Yersinia pestis |
General Information | Comment | Organism |
---|---|---|
physiological function | cleavage of Yersinia pestis autotransporter YapE by protease Pla is required to mediate bacterial aggregation and adherence to eukaryotic cells. Post-translation modification of YapE appears to be specific to Yersinia pestis. It was acquired along with the acquisition ofplasmid pPCP1 during the divergence of Yersinia pestis from Yersinia pseudotuberculosis, and is the first evidence of a mechanism to regulate bacterial adherence | Yersinia pestis |