Crystallization (Comment) | Organism |
---|---|
molecular dynamics simulations in complerx with inhibitors amprenvir and darunavir | HIV-2 subtype A |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amprenavir | inhibitor binds less strongly to HIV-2 protease than to HIV-2 protease due to a reduction of the van der Waals interactions. Inhibitor binding tends to make the flaps of PR2 close and the one of PR1 open | HIV-2 subtype A | |
darunavir | inhibitor binds less strongly to HIV-2 protease than to HIV-2 protease due to a reduction of the van der Waals interactions. Inhibitor binding tends to make the flaps of PR2 close and the one of PR1 open | HIV-2 subtype A |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
HIV-2 subtype A | P04584 | - |
- |