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Literature summary for 3.4.23.47 extracted from

  • Lescar, J.; Brynda, J.; Rezacova, P.; Stouracova, R.; Riottot, M.M.; Chitarra, V.; Fabry, M.; Horejsi, M.; Sedlacek, J.; Bentley, G.A.
    Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody (1999), Protein Sci., 8, 2686-2696.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine
-
Human immunodeficiency virus 2

Cloned(Commentary)

Cloned (Comment) Organism
cloned and expressed in Escherichia coli BL21(DE3) Human immunodeficiency virus 2

Inhibitors

Inhibitors Comment Organism Structure
monoclonal antibody 1696
-
Human immunodeficiency virus 2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GAG precursor protein of HIV-2 + H2O Human immunodeficiency virus 2
-
?
-
?

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 2
-
human immunodeficiency virus type 2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GAG precursor protein of HIV-2 + H2O
-
Human immunodeficiency virus 2 ?
-
?

Subunits

Subunits Comment Organism
dimer 2 identical subunits, homodimer Human immunodeficiency virus 2