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Literature summary for 3.4.23.46 extracted from

  • Augustin, S.; Huebbe, P.; Matzner, N.; Augustin, K.; Schliebs, R.; Cermak, R.; Wolffram, S.; Rimbach, G.
    Ginkgo biloba extract and its flavonol and terpenelactone fractions do not affect beta-secretase mRNA and enzyme activity levels in cultured neurons and in mice (2008), Planta Med., 74, 6-13.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
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Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information in wild-type as well as transgenic Tg2576 mice, no effect on BACE-1 activity can be observed by standardized Ginkgo biloba extract EGb761, a flavonol fraction or a terpenelactone fraction from Ginkgo biloba leaf; neither standardized Ginkgo biloba extract EGb761, a flavonol fraction or a terpenelactone fraction from Ginkgo biloba leaf affect BACE-1 activity in vitro or in Neuro-2a cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation recombinant enzyme Homo sapiens
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