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Literature summary for 3.4.23.46 extracted from

  • Stockley, J.H.; O'Neill, C.
    The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimers disease brain (2007), Biochem. Soc. Trans., 35, 574-576.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens P56817
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-

Source Tissue

Source Tissue Comment Organism Textmining
brain
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Homo sapiens
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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overview about dysregulation of BACE1 expression and activity in normal and Alzheimer brains, comparative analyses performed on BACE1 activities and protein levels in control and Alzheimer disease brain summarized, substrate with Swedish mutation of amyloid precursor protein APP and with wild-type amyloid precursor protein APP regarded, different brain regions considered, differences between BACE1 and BACE2 summarized Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information overview about investigations of BACE1 protein levels and beta-secretase activity in control and Alzheimer disease brain under consideration of expression of BACE2 in the human brain Homo sapiens ?
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?

Synonyms

Synonyms Comment Organism
BACE1
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Homo sapiens
beta-secretase
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Homo sapiens