Literature summary for 3.4.23.46 extracted from

Kitazume, S.; Tachida, Y.; Oka, R.; Kotani, N.; Ogawa, K.; Suzuki, M.; Dohmae, N.; Takio, K.; Saido, T.C.; Hashimoto, Y.
Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase (BACE1) (2003), J. Biol. Chem., 278, 14865-14871.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
amyloid precursor protein + H2O	-	Homo sapiens	?	-	?
ST6Gal I + H2O	i.e. membrane-bound alpha2,6-sialyltransferase, cleavage occurs between Leu37 and Gln38	Homo sapiens	?	-	?
Swedish variant of amyloid precursor protein + H2O	-	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)