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Literature summary for 3.4.23.44 extracted from

  • Zlotnick, A.; Reddy, V.S.; Dasgupta, R.; Schneemann, A.; Ray,W.J.; Rueckert, R.R.; Johnson, J.E.
    Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue (1994), J. Biol. Chem., 269, 13680-13684.
    View publication on PubMed
Search for more literature for 3.4.23.44

Cloned(Commentary)

Cloned (Comment) Organism
-
 black beetle virus
-
 Flock house virus

Protein Variants

Protein Variants Comment Organism
D75E no maturation cleavage Flock house virus
D75N no maturation cleavage Flock house virus
D75T no maturation cleavage Flock house virus
D75V no maturation cleavage Flock house virus
N363T drastically slowed cleavage Flock house virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nodavirus provirion + H2O black beetle virus maturation of noninfectious nodavirus provirions by autoproteolytic cleavage of the alpha-protein, producing the beta-protein with a C-terminal Asn636, and a gamma-peptide with an N-terminal Ala nodavirus mature virion
-
 ?
nodavirus provirion + H2O Flock house virus maturation of noninfectious nodavirus provirions by autoproteolytic cleavage of the alpha-protein, producing the beta-protein with a C-terminal Asn636, and a gamma-peptide with an N-terminal Ala nodavirus mature virion
-
 ?

Organism

Organism UniProt Comment Textmining
black beetle virus
-
-
-
Flock house virus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nodavirus provirion + H2O maturation of noninfectious nodavirus provirions by autoproteolytic cleavage of the alpha-protein, producing the beta-protein with a C-terminal Asn636, and a gamma-peptide with an N-terminal Ala black beetle virus nodavirus mature virion
-
 ?
nodavirus provirion + H2O maturation of noninfectious nodavirus provirions by autoproteolytic cleavage of the alpha-protein, producing the beta-protein with a C-terminal Asn636, and a gamma-peptide with an N-terminal Ala Flock house virus nodavirus mature virion
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
-
 Flock house virus