Literature summary for 3.4.23.39 extracted from

Moon, R.P.; Bur, D.; Loetscher, H.; D'Arcy, A.; Tyas, L.; Oefner, C.; Grueninger-Leitch, F.; Mona, D.; Rupp, K.; Dorn, A.; Matile, H.; Certa, U.; Berry, C.; Kay, J.; Ridley, R.G.
Studies on plasmepsins I and II from the malarial parasite Plasmodium falciparum and their exploitation as drug targets (1998), Adv. Exp. Med. Biol., 436, 397-406.

Search for more literature for 3.4.23.39

Crystallization (Commentary)

Crystallization (Comment)	Organism
plasmepsin II in complex with pepstatin A	Plasmodium falciparum

Inhibitors

Inhibitors	Comment	Organism	Structure
Ro40-4388	-	Plasmodium falciparum
Ro40-5576	-	Plasmodium falciparum

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	recombinant proplasmepsin II autoactivates at acidic pH, but the location of the cleavage site varies dependening on the conditions used	Plasmodium falciparum

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00025	-	Ro40-5576	-	Plasmodium falciparum
0.0007	-	Ro40-4388	-	Plasmodium falciparum

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)