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Literature summary for 3.4.23.38 extracted from

  • Francis, S.E.; Banerjee, R.; Goldberg, D.E.
    Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II (1997), J. Biol. Chem., 272, 14961-14968.
    View publication on PubMed
Search for more literature for 3.4.23.38

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane proplasmepsin I is a type II integral membrane protein that is transported though the secretory pathway before cleavage to the soluble form Plasmodium falciparum 16020
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vacuole
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 Plasmodium falciparum 5773
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Plasmodium falciparum plasmepsin I is synthesized and processed to the mature form soon after the parasite invades the red blood cell ?
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 ?

Organism

Organism UniProt Comment Textmining
Plasmodium falciparum
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Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification proplasmepsin maturation appears to require acidic conditions, proplasmepsin maturation may not be autocatalytic in vivo Plasmodium falciparum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information plasmepsin I is synthesized and processed to the mature form soon after the parasite invades the red blood cell Plasmodium falciparum ?
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 ?