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Literature summary for 3.4.23.34 extracted from

  • Athauda, S.B.P.; Arakawa, H.; Nishigai, M.; Takahashi, T.; Takahashi, K.
    Inhibition of cathepsin E by alpha 2-macroglobulin and the resulting structural changes in the inhibitor (1993), J. Biochem., 113, 526-530.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
alpha2-Macroglobulin at pH 5.5, RNAse as substrate, at a molar ratio of enzyme/inhibitor of 0.5:1 to 2:1, above a ratio of 2:1 the excess enzyme is not inhibited, structural changes in alpha2-macroglobulin upon complex formation, no inhibition with oxidized insulin B-chain as substrate Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastric mucosa
-
Homo sapiens
-
stomach
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Oxidized insulin B-chain + H2O
-
Homo sapiens Hydrolyzed oxidized insulin B-chain
-
?
Reduced and carboxymethylated bovine pancreatic ribonuclease A + H2O
-
Homo sapiens Hydrolyzed bovine pancreatic RCm ribonuclease A
-
?