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Literature summary for 3.4.23.24 extracted from

  • Gabrielli, E.; Sabbatini, S.; Roselletti, E.; Kasper, L.; Perito, S.; Hube, B.; Cassone, A.; Vecchiarelli, A.; Pericolini, E.
    In vivo induction of neutrophil chemotaxis by secretory aspartyl proteinases of Candida albicans (2016), Virulence, 7, 819-825 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
pepstatin A strong inhibitor; strong inhibitor Candida albicans

Organism

Organism UniProt Comment Textmining
Candida albicans P0DJ06
-
-
Candida albicans Q5AC08
-
-

Synonyms

Synonyms Comment Organism
SAP2 isoform Candida albicans
SAP6 isoform Candida albicans
secretory aspartyl proteinase
-
Candida albicans

General Information

General Information Comment Organism
physiological function isoform Sap2 induces neutrophil migration and production of potent chemoattractive chemokines such as interleukin-8 and macrophage inflammatory protein-2 by vaginal epithelial cells Candida albicans
physiological function isoform Sap6 induces neutrophil migration and production of potent chemoattractive chemokines such as interleukin-8 and macrophage inflammatory protein-2 by vaginal epithelial cells Candida albicans