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Literature summary for 3.4.23.24 extracted from
- X-ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from Candida albicans (2008), Proteins, 272, 1308-1319.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Pichia pastoris | Candida albicans |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| Sap3 with PepA in the presence of 10 mM zinc acetate, Sap3 without PepA in the presence of 0.2M potassium bromide, 15% PEG4000 and 0.1 M cacodylic acid/NaOH, pH 6.5. The Sap3 protein crystallizes in the trigonal space group P3(2)21 containing one molecule per asymmetric unit. | Candida albicans |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| pepstatin A | - |
Candida albicans |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida albicans | P0CY29 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| anion exchange chromatography | Candida albicans |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| culture supernatant | - |
Candida albicans | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| aspartic proteinase 3 | - |
Candida albicans |
| SAP3 | - |
Candida albicans |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.017 | - |
pepstatin A | - |
Candida albicans | |
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Release 2023.1 (January 2023)
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