Protein Variants | Comment | Organism |
---|---|---|
D30N | the mutation is associated with decreased susceptibility to protease inhibitor nelfinavir | Human immunodeficiency virus 1 |
F53L | the mutation is associated with decreased susceptibility to protease inhibitor saquinavir | Human immunodeficiency virus 1 |
G48V | the mutation is associated with decreased susceptibility to protease inhibitor saquinavir and nelfinavir | Human immunodeficiency virus 1 |
G73S | the mutation is associated with decreased susceptibility to protease inhibitors saquinavir, indinavir and nelfinavir | Human immunodeficiency virus 1 |
I47AV | the mutation is associated with decreased susceptibility to protease inhibitors atazanavir and lopinavir | Human immunodeficiency virus 1 |
I47V | the mutation is associated with decreased susceptibility to protease inhibitors darunavir and tipranavir | Human immunodeficiency virus 1 |
I50V | the mutation is associated with decreased susceptibility to protease inhibitors atazanavir, darunavir and lopinavir | Human immunodeficiency virus 1 |
I54AMV | the mutation is associated with decreased susceptibility to protease inhibitor tipranavir | Human immunodeficiency virus 1 |
I54LM | the mutation is associated with decreased susceptibility to protease inhibitor atazanavir and darunavir | Human immunodeficiency virus 1 |
I54LMV | the mutation is associated with decreased susceptibility to protease inhibitor lopinavir | Human immunodeficiency virus 1 |
I54TV | the mutation is associated with decreased susceptibility to protease inhibitor saquinavir | Human immunodeficiency virus 1 |
I54V | the mutation is associated with decreased susceptibility to protease inhibitors indinavir and nelfinavir | Human immunodeficiency virus 1 |
I84AV | the mutation is associated with decreased susceptibility to protease inhibitor atazanavir, saquinavir, indinavir, lopinavir and nelfinavir | Human immunodeficiency virus 1 |
I84V | the mutation is associated with decreased susceptibility to protease inhibitors darunavir and tipranavir | Human immunodeficiency virus 1 |
K43T | the mutation is associated with decreased susceptibility to protease inhibitor tipranavir | Human immunodeficiency virus 1 |
L10F | the mutation is associated with decreased susceptibility to protease inhibitors atazanavir, lopinavir and indinavir | Human immunodeficiency virus 1 |
L10FI | the mutation is associated with decreased susceptibility to protease inhibitor nelfinavir | Human immunodeficiency virus 1 |
L24I | the mutation is associated with decreased susceptibility to protease inhibitors lopinavir and indinavir | Human immunodeficiency virus 1 |
L33F | the mutation is associated with decreased susceptibility to protease inhibitors atazanavir, darunavir, tipranavir and lopinavir | Human immunodeficiency virus 1 |
L76V | the mutation is associated with decreased susceptibility to protease inhibitors atazanavir, darunavir, indinavir and lopinavir | Human immunodeficiency virus 1 |
L89V | the mutation is associated with decreased susceptibility to protease inhibitor darunavir | Human immunodeficiency virus 1 |
L90M | the mutation is associated with decreased susceptibility to protease inhibitors saquinavir, indinavir and nelfinavir | Human immunodeficiency virus 1 |
M46IL | the mutation is associated with decreased susceptibility to protease inhibitors atazanavir, nelfinavir, indinavir and lopinavir | Human immunodeficiency virus 1 |
N83D | the mutation is associated with decreased susceptibility to protease inhibitor tipranavir | Human immunodeficiency virus 1 |
N88DS | the mutation is associated with decreased susceptibility to protease inhibitor nelfinavir | Human immunodeficiency virus 1 |
N88S | the mutation is associated with decreased susceptibility to protease inhibitor indinavir | Human immunodeficiency virus 1 |
T74P | the mutation is associated with decreased susceptibility to protease inhibitors darunavir and tipranavir | Human immunodeficiency virus 1 |
V32I | the mutation is associated with decreased susceptibility to protease inhibitors atazanavir, darunavir, lopinavir and indinavir | Human immunodeficiency virus 1 |
V82AFST | the mutation is associated with decreased susceptibility to protease inhibitor lopinavir | Human immunodeficiency virus 1 |
V82F | the mutation is associated with decreased susceptibility to protease inhibitors atazanavir and nelfinavir | Human immunodeficiency virus 1 |
V82LT | the mutation is associated with decreased susceptibility to protease inhibitor tipranavir | Human immunodeficiency virus 1 |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
atazanavir | - |
Human immunodeficiency virus 1 | |
darunavir | - |
Human immunodeficiency virus 1 | |
fosamprenavir | - |
Human immunodeficiency virus 1 | |
indinavir | - |
Human immunodeficiency virus 1 | |
lopinavir | - |
Human immunodeficiency virus 1 | |
nelfinavir | - |
Human immunodeficiency virus 1 | |
saquinavir | - |
Human immunodeficiency virus 1 | |
tipranavir | - |
Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
HIV-1 protease | - |
Human immunodeficiency virus 1 |