Literature summary for 3.4.23.16 extracted from

Hu, G.D.; Zhu, T.; Zhang, S.L.; Wang, D.; Zhang, Q.G.
Some insights into mechanism for binding and drug resistance of wild type and I50V V82A and I84V mutations in HIV-1 protease with GRL-98065 inhibitor from molecular dynamic simulations (2010), Eur. J. Med. Chem., 45, 227-235.

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Protein Variants

Protein Variants	Comment	Organism
I50V	key residue mutation of drug resistance	Human immunodeficiency virus 1
I84V	key residue mutation of drug resistance	Human immunodeficiency virus 1
V82A	key residue mutation of drug resistance	Human immunodeficiency virus 1

Inhibitors

Inhibitors	Comment	Organism	Structure
GRL-98065	I50V, V82A and I84V mutant proteins show high levels of resistence	Human immunodeficiency virus 1

Organism

Organism	UniProt	Comment	Textmining
Human immunodeficiency virus 1	-	-	-

Synonyms

Synonyms	Comment	Organism
HIV-1 protease	-	Human immunodeficiency virus 1

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Release 2023.1 (January 2023)