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Literature summary for 3.4.23.16 extracted from
- Structural analysis of human immunodeficiency virus type 1 CRF01_AE protease in complex with the substrate p1-p6 (2008), J. Virol., 82, 6762-6766.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Human immunodeficiency virus 1 |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| in complex with substrate Arg-Pro-Gly-Asn-Phe-Leu-Gln-Ser-Arg-Pro, to 2.8 A resolution. Hydrogen bonding between the flap hinge and the protease core regions shows significant structural rearrangements in CRF01_AE protease compared to the clade B protease structure | Human immunodeficiency virus 1 |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human immunodeficiency virus 1 | Q90VT5 | Gag polyprotein | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Arg-Pro-Gly-Asn-Phe-Leu-Gln-Ser-Arg-Pro + H2O | decameric p1-p6 peptide | Human immunodeficiency virus 1 | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CRF01_AE protease | - |
Human immunodeficiency virus 1 |
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