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Literature summary for 3.4.23.16 extracted from

  • Schramm, H.J.; Billich, A.; Jaeger, E.; Rucknagel, K.P.; Arnold, G.; Schramm, W.
    The inhibition of HIV-1 protease by interface peptides (1993), Biochem. Biophys. Res. Commun., 194, 595-600.
    View publication on PubMed
Search for more literature for 3.4.23.16

Inhibitors

Inhibitors Comment Organism Structure
Ac-HMSFNL IC50: 0.19 mM Human immunodeficiency virus 1
Ac-HMTLNF
-
 Human immunodeficiency virus 1
Ac-HTLNF
-
 Human immunodeficiency virus 1
Ac-IGLTLNF
-
 Human immunodeficiency virus 1
Ac-LTLNF
-
 Human immunodeficiency virus 1
Ac-QIGMTLNF IC50: 0.44 mM Human immunodeficiency virus 1
Ac-TLNF IC50: 1.5 mM Human immunodeficiency virus 1
Ac-TLNF-NH2 IC50 is above 2 mM Human immunodeficiency virus 1
Ac-TVSFNF IC50: 0.08 mM Human immunodeficiency virus 1
Arg-Leu-Asn-Phe IC50: 0.87 mM Human immunodeficiency virus 1
IGRNLLTQIGCTLNF IC50: 0.41 mM Human immunodeficiency virus 1
LTLNF
-
 Human immunodeficiency virus 1
MTLNF
-
 Human immunodeficiency virus 1
RTLNLGL IC50 is above 0.8 mM Human immunodeficiency virus 1
Ser-Leu-Asn-Phe IC50: 0.47 mM Human immunodeficiency virus 1
SFNL IC50: 0.28 mM Human immunodeficiency virus 1
SFNLE IC50: 0.31 mM Human immunodeficiency virus 1
Thr-Leu-Asn-Leu IC50: 0.38 mM Human immunodeficiency virus 1
Thr-Leu-Asn-Phe-NH2 IC50 is above 2 mM Human immunodeficiency virus 1
Thr-Leu-Asn-Tyr IC50 is about 1 mM Human immunodeficiency virus 1
Thr-Phe-Asn-Phe IC50: 0.45 mM Human immunodeficiency virus 1
TLNLGF IC50 is above 0.8 mM Human immunodeficiency virus 1

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1
-
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.08
-
 IC50: 0.08 mM Human immunodeficiency virus 1 Ac-TVSFNF
0.19
-
 IC50: 0.19 mM Human immunodeficiency virus 1 Ac-HMSFNL
0.28
-
 IC50: 0.28 mM Human immunodeficiency virus 1 SFNL
0.31
-
 IC50: 0.31 mM Human immunodeficiency virus 1 SFNLE
0.38
-
 IC50: 0.38 mM Human immunodeficiency virus 1 Thr-Leu-Asn-Leu
0.41
-
 IC50: 0.41 mM Human immunodeficiency virus 1 IGRNLLTQIGCTLNF
0.44
-
 IC50: 0.44 mM Human immunodeficiency virus 1 Ac-QIGMTLNF
0.45
-
 IC50: 0.45 mM Human immunodeficiency virus 1 Thr-Phe-Asn-Phe
0.47
-
 IC50: 0.47 mM Human immunodeficiency virus 1 Ser-Leu-Asn-Phe
0.8
-
 IC50 is above 0.8 mM Human immunodeficiency virus 1 RTLNLGL
0.8
-
 IC50 is above 0.8 mM Human immunodeficiency virus 1 TLNLGF
0.87
-
 IC50: 0.87 mM Human immunodeficiency virus 1 Arg-Leu-Asn-Phe
1
-
 IC50 is about 1 mM Human immunodeficiency virus 1 Thr-Leu-Asn-Tyr
1.5
-
 IC50: 1.5 mM Human immunodeficiency virus 1 Ac-TLNF
2
-
 IC50 is above 2 mM Human immunodeficiency virus 1 Ac-TLNF-NH2
2
-
 IC50 is above 2 mM Human immunodeficiency virus 1 Thr-Leu-Asn-Phe-NH2