Literature summary for 3.4.23.15 extracted from

Moutzouri, E.; Florentin, M.; Elisaf, M.S.; Mikhailidis, D.P.; Liberopoulos, E.N.
Aliskiren, a directrenin inhibitor, in clinical practice: a new approach in the treatment of hypertension (2010), Curr. Vasc. Pharmacol., 8, 344-362.

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Inhibitors

Inhibitors	Comment	Organism	Structure
aliskiren	direct renin inhibitor for the treatment of hypertension	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
angiotensinogen + H2O	Homo sapiens	-	angiotensin I + angiotensinogen propeptide	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
juxtaglomerular apparatus	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
angiotensinogen + H2O	-	Homo sapiens	angiotensin I + angiotensinogen propeptide	-	?

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Release 2023.1 (January 2023)