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Literature summary for 3.4.23.15 extracted from

  • Ferrari, P.; Shaw, S.G.; Nicod, J.; Saner, E.; Nussberger, J.
    Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism (2004), J. Hypertens., 22, 377-381.
    View publication on PubMed

Application

Application Comment Organism
diagnostics the plasma aldosterone-to-renin ratio measuring plasma renin activity, PRA, is used for screening of primary aldosteronism Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular plasma Homo sapiens
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-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensinogen + H2O Homo sapiens plasma aldosterone-to-renin ratio thresholds in plasma of healthy persons, patients with hypertension and those with additional adrenal adenomas, overview angiotensin I + angiotensinogen propeptide
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma determination of plasma aldosterone-to-renin ratio thresholds in plasma of healthy persons, patients with hypertension and those with additional adrenal adenomas, overview Homo sapiens
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
renin activity in plasma of healthy persons, patients with hypertension and those with additional adrenal adenomas, overview Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensinogen + H2O
-
Homo sapiens angiotensin I + angiotensinogen propeptide
-
?
angiotensinogen + H2O plasma aldosterone-to-renin ratio thresholds in plasma of healthy persons, patients with hypertension and those with additional adrenal adenomas, overview Homo sapiens angiotensin I + angiotensinogen propeptide
-
?