Literature summary for 3.4.22.B79 extracted from

Ramphan, S.; Khongwichit, S.; Saisawang, C.; Kovanich, D.; Ketterman, A.J.; Ubol, S.; Auewarakul, P.; Roytrakul, S.; Smith, D.R.; Kuadkitkan, A.
Ubiquitin-conjugating enzyme E2 L3 is downregulated by the chikungunya virus nsP2 protease (2018), Proteomics Clin. Appl., 12, e1700020 .

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Organism

Organism	UniProt	Comment	Textmining
Chikungunya virus	A0A0E3MZW7	nonstructural polyprotein	-

General Information

General Information	Comment	Organism
physiological function	upon transfection of HeLa cells, 21 differentially regulated (six upregulated, 15 downregulated) spots are observed. Ubiquitin-conjugating enzyme UBE2L3 is downregulated. Transfection of full length UBE2L3 into HEK293T/17 cells prior to CHIKV infection reduces levels of infection but does not alter RNA genome levels	Chikungunya virus

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Release 2023.1 (January 2023)