Literature summary for 3.4.22.B74 extracted from

Mukhopadhyay, D.; Arnaoutov, A.; Dasso, M.
The SUMO protease SENP6 is essential for inner kinetochore assembly (2010), J. Cell Biol., 188, 681-692.

Search for more literature for 3.4.22.B74

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
SENP6	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	cells lacking SENP6 show defects in spindle assembly and metaphase chromosome congression. A subset of proteins becomes undetectable on inner kinetochores after SENP6 depletion, particularly the CENP-H/I/K complex	Homo sapiens
physiological function	SENP6 is essential for inner kinetochore assembly. Balanced activities of SENP6 and RNF4 control vertebrate kinetochore assembly through SUMO-targeted destabilization of inner plate components	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)