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Literature summary for 3.4.22.B66 extracted from

  • Wang, P.; Arjona, A.; Zhang, Y.; Sultana, H.; Dai, J.; Yang, L.; LeBlanc, P.M.; Doiron, K.; Saleh, M.; Fikrig, E.
    Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I (2010), Nat. Immunol., 11, 912-919.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
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Mus musculus
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MEF cell
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Mus musculus
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General Information

General Information Comment Organism
physiological function caspase-12 plays a role in controlling West Nile virus viral infection via the pattern recognition receptor RIG-I. Caspase-12 positively modulates the production of type I interferon by regulating E3 ubiquitin ligase TRIM25-mediated ubiquitination of RIG-I Mus musculus