Literature summary for 3.4.22.B49 extracted from

Ortega-Vargas, S.; Espitia, C.; Sahagun-Ruiz, A.; Parada, C.; Balderas-Loaeza, A.; Villa-Mancera, A.; Quiroz-Romero, H.
Moderate protection is induced by a chimeric protein composed of leucine aminopeptidase and cathepsin L1 against Fasciola hepatica challenge in sheep (2019), Vaccine, 37, 3234-3240 .

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Cloned(Commentary)

Cloned (Comment)	Organism
recombinant expression of His-tagged chimeric mutant from leucine aminopeptidase (FhLAP) and cathepsin L1 (FhCL1) of Fasciola hepatica in Escherichia coli strain Rosetta (DE3)	Fasciola hepatica

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of a chimeric protein from leucine aminopeptidase (FhLAP) and cathepsin L1 (FhCL1) of Fasciola hepatica. The chimeric mutant protein with Quil A adjuvant is used for vaccination of Katahdin x East Friesian male sheep	Fasciola hepatica

Organism

Organism	UniProt	Comment	Textmining
Fasciola hepatica	Q9GRW5	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant His-tagged chimeric mutant from Escherichia coli strain Rosetta (DE3) by nickel affinity chromatography and dialysis	Fasciola hepatica

Synonyms

Synonyms	Comment	Organism
FhCL1	-	Fasciola hepatica

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Release 2023.1 (January 2023)