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Literature summary for 3.4.22.B49 extracted from

  • Robinson, M.W.; Tort, J.F.; Lowther, J.; Donnelly, S.M.; Wong, E.; Xu, W.; Stack, C.M.; Padula, M.; Herbert, B.; Dalton, J.P.
    Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors (2008), Mol. Cell. Proteomics, 7, 1111-1123.
    View publication on PubMed
Search for more literature for 3.4.22.B49

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.003
-
 benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin 37°C, pH 7.3 Fasciola hepatica
0.0036
-
 benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin 37°C, pH 7.3 Fasciola hepatica
0.0044
-
 benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin 37°C, pH 5.5 Fasciola hepatica
0.0242
-
 benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin 37°C, pH 5.5 Fasciola hepatica
0.1819
-
 benzyloxycarbonyl-Pro-Arg-7-amido-4-methylcoumarin 37°C, pH 7.3 Fasciola hepatica
0.1912
-
 benzyloxycarbonyl-Pro-Arg-7-amido-4-methylcoumarin 37°C, pH 5.5 Fasciola hepatica

Organism

Organism UniProt Comment Textmining
Fasciola hepatica Q7JNQ9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin + H2O
-
 Fasciola hepatica benzyloxycarbonyl-Leu-Arg + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Fasciola hepatica benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-Pro-Arg-7-amido-4-methylcoumarin + H2O
-
 Fasciola hepatica benzyloxycarbonyl-Pro-Arg + 7-amino-4-methylcoumarin
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1
-
 benzyloxycarbonyl-Pro-Arg-7-amido-4-methylcoumarin 37°C, pH 5.5 Fasciola hepatica
1.7
-
 benzyloxycarbonyl-Pro-Arg-7-amido-4-methylcoumarin 37°C, pH 7.3 Fasciola hepatica
2
-
 benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin 37°C, pH 7.3 Fasciola hepatica
11
-
 benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin 37°C, pH 7.3 Fasciola hepatica
24.7
-
 benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin 37°C, pH 5.5 Fasciola hepatica
36.5
-
 benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin 37°C, pH 5.5 Fasciola hepatica