Literature summary for 3.4.22.B49 extracted from

Kesik, M.; Jedlina-Panasiuk, L.; Kozak-Cieszczyk, M.; P?ucienniczak, A.; Wedrychowicz, H.
Enteral vaccination of rats against Fasciola hepatica using recombinant cysteine proteinase (cathepsin L1) (2007), Vaccine, 25, 3619-3628.

Search for more literature for 3.4.22.B49

Application

Application	Comment	Organism
medicine	enteral vaccination of rats against Fasciola hepatica using recombinant cysteine proteinase (cathepsin L1). The mature CPFhW protein is the enzyme secreted by Fasciola hepatica with which the host organism has contact. This can explain why immunisation with this antigen resultes in best protection in challenged animals, especially in comparison to the immature form of the CPFhW protein. Substantial protection can be obtained when the antigen is given with food. Oral administration of the antigen does not lead to decreasing of the level of protection compared with intragastric administration	Fasciola hepatica

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Fasciola hepatica

Organism

Organism	UniProt	Comment	Textmining
Fasciola hepatica	-	-	-

Renatured (Commentary)

Renatured (Comment)	Organism
-	Fasciola hepatica

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzyloxycarbonyl-Phe-Phe-Arg-7-amido-4-methylcoumarin + H2O	renatured CPFhW	Fasciola hepatica	?	-	?
additional information	renatured enzyme shows no activity with benzyloxycarbonyl-Phe-Arg-beta-naphthylamide	Fasciola hepatica	?	-	?

Synonyms

Synonyms	Comment	Organism
CPFhW	-	Fasciola hepatica

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Release 2023.1 (January 2023)