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Literature summary for 3.4.22.B30 extracted from
- Calpain-10: from genome search to function (2005), Diabetes Metab. Res. Rev., 21, 505-514.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Homo sapiens |  |
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | calpain-10 is the first diabetes gene that can be identified through a genome scan | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| calpastatin | - |
Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
| membrane | - |
Homo sapiens | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | enhances activity | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 54000 | - |
monomer, binds to SNAP-25 and syntaxin 1 in beta-cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9HC96 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreatic beta cell | - |
Homo sapiens | - |
| skeletal muscle | - |
Homo sapiens | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | - |
Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calpain-10 | - |
Homo sapiens |
| CAPN10 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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