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Literature summary for 3.4.22.B27 extracted from

  • Osako, Y.; Maemoto, Y.; Tanaka, R.; Suzuki, H.; Shibata, H.; Maki, M.
    Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction (2010), FEBS J., 277, 4412-4426.
    View publication on PubMed
Search for more literature for 3.4.22.B27

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK293T cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
C290A active site mutant Homo sapiens
C290S the mutant shows no autolytic activity Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
increased sodium tolerance-1 protein + H2O Homo sapiens
-
 ?
-
 ?
additional information Homo sapiens GST-MIM protein enhances the autolysis of purified Strep-tagged monomeric green fluorescent protein-fused calpain 7. Calpain 7 is activated in the endosomal sorting complex required for transport system ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9Y6W3
-
-

Purification (Commentary)

Purification (Comment) Organism
glutathione-Sepharose beads chromatography and Strep-Tactin Sepharose beads chromatography Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
increased sodium tolerance-1 protein + H2O
-
 Homo sapiens ?
-
 ?
additional information GST-MIM protein enhances the autolysis of purified Strep-tagged monomeric green fluorescent protein-fused calpain 7. Calpain 7 is activated in the endosomal sorting complex required for transport system Homo sapiens ?
-
 ?