Literature summary for 3.4.22.B24 extracted from

Rosenberger, G.; Gal, A.; Kutsche, K.
AlphaPIX associates with calpain 4, the small subunit of calpain, and has a dual role in integrin-mediated cell spreading (2005), J. Biol. Chem., 280, 6879-6889.

Search for more literature for 3.4.22.B24

Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
calpain inhibitor IV	0.1 mg/ml, irreversible, attacks the active site of m-calpain nucleophilically, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired	Homo sapiens
calpeptin	0.075 mg/ml, reversible, reacts with the active site of both my-calpain and m-calpain, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired	Homo sapiens
PD 151746	0.1 mg/ml, reversible, binds predominantly to the Ca2+-binding site of my-calpain, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
additional information	around the nucleus, colocalizes with alpha-p21-activated kinase interacting exchange factor (alpha-PIX)	Homo sapiens	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
testis	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
calpain 4	-	Homo sapiens

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Release 2023.1 (January 2023)