Literature summary for 3.4.22.B19 extracted from

Wiley, D.J.; Shrestha, N.; Yang, J.; Atis, N.; Dayton, K.; Schesser, K.
The activities of the Yersinia protein kinase A (YpkA) and outer protein J (YopJ) virulence factors converge on an eIF2alpha kinase (2009), J. Biol. Chem., 284, 24744-24753.

Search for more literature for 3.4.22.B19

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Schizosaccharomyces pombe	Yersinia pestis

Protein Variants

Protein Variants	Comment	Organism
C172A	inactive	Yersinia pestis

Organism

Organism	UniProt	Comment	Textmining
Yersinia pestis	-	-	-

Synonyms

Synonyms	Comment	Organism
Yersinia outer protein J	-	Yersinia pestis
YopJ	-	Yersinia pestis

General Information

General Information	Comment	Organism
physiological function	when expressed in Schizosaccharomyces pombe, YopJ sensitizes cells to osmotic and oxidative stresses through a Hri2-dependent mechanism, however, when co-expressed with Yersinia protein kinase A, YopJ protects cells from Yersinia protein kinase A-mediated toxicity, and this protection is entirely dependent on Hri2. YopJ does not confer protection against the toxic effects of the Yersinia virulence factor YopE	Yersinia pestis

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Release 2023.1 (January 2023)