Cloned (Comment) | Organism |
---|---|
SrtADELTA24 is expressed in Escherichia coli | Staphylococcus aureus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
galangin | IC50 for recombinant SrtB(DELTA30): 0.03837 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
galangin-3-methyl ether | IC50 for recombinant SrtB(DELTA30): 0.1136 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
isorhamnetin | IC50 for recombinant SrtB(DELTA30): 0.04335 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
kaempferol | IC50 for recombinant SrtB(DELTA30): 0.02455 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
morin | IC50 for recombinant SrtB(DELTA30): 0.00854 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
myricetin | IC50 for recombinant SrtB(DELTA30): 0.03689 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
quercetin | IC50 for recombinant SrtB(DELTA30): 0.03328 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | |
quercetin-3,3'-dimethyl ether | IC50 for recombinant SrtB(DELTA30): 0.0603 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
- |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00854 | - |
IC50 for recombinant SrtB(DELTA30): 0.00854 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | morin | |
0.02455 | - |
IC50 for recombinant SrtB(DELTA30): 0.02455 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | kaempferol | |
0.03328 | - |
IC50 for recombinant SrtB(DELTA30): 0.03328 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | quercetin | |
0.03689 | - |
IC50 for recombinant SrtB(DELTA30): 0.03689 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | myricetin | |
0.03837 | - |
IC50 for recombinant SrtB(DELTA30): 0.03837 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | galangin | |
0.04335 | - |
IC50 for recombinant SrtB(DELTA30): 0.04335 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | isorhamnetin | |
0.0603 | - |
IC50 for recombinant SrtB(DELTA30): 0.0603 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | quercetin-3,3'-dimethyl ether | |
0.1136 | - |
IC50 for recombinant SrtB(DELTA30): 0.1136 mM, no antibacterial activity against Staphylococcus aureus | Staphylococcus aureus | galangin-3-methyl ether |