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Literature summary for 3.4.22.70 extracted from

  • Mazmanian, S.K.; Liu, G.; Ton-That, H.; Schneewind, O.
    Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall (1999), Science, 285, 760-763.
    View publication on PubMed

Application

Application Comment Organism
medicine in principle the purified SrtA protein can be used to screen for compounds that inhibit cell wall sorting, a strategy that may lead to new therapies for human infections caused by Gram-positive bacteria Staphylococcus aureus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Staphylococcus aureus the enzyme anchors surface proteins to the bacterial cells wall ?
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?

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus Q9S446
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme anchors surface proteins to the bacterial cell wall Staphylococcus aureus ?
-
?
additional information the enzyme anchors surface proteins to the bacterial cells wall Staphylococcus aureus ?
-
?