Literature summary for 3.4.22.69 extracted from

Zhang, X.W.; Yap, Y.L.
Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs (2004), Bioorg. Med. Chem., 12, 2517-2521.

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Organism

Organism	UniProt	Comment	Textmining
Severe acute respiratory syndrome-related coronavirus	-	-	-

Synonyms

Synonyms	Comment	Organism
SARS CoV main proteinase	-	Severe acute respiratory syndrome-related coronavirus

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
6e-18	-	promazine	in silico binding studies	Severe acute respiratory syndrome-related coronavirus
8.7e-17	-	lopinavir	in silico binding studies	Severe acute respiratory syndrome-related coronavirus
2.1e-16	-	N-[3-[(E)-(tert-butoxyimino)methyl]-4-chlorophenyl]-2-methylfuran-3-carboxamide	in silico binding studies	Severe acute respiratory syndrome-related coronavirus

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Release 2023.1 (January 2023)