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Literature summary for 3.4.22.64 extracted from
- Caspase-11 contributes to oviduct pathology during genital Chlamydia infection in mice (2019), Infect. Immun., 87, e00262 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P70343 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | caspase-11 deficiency shows the same effect as the combined absence of both caspase-1 and caspase-11 on oviduct pathology. Caspase-11-deficient mice show reduced dilation in both the oviducts and uterus. In the caspase-11-deficient mice, increased chlamydial burdens are observed in the upper genital tract, which correlate with increased CD4 T cell recruitment. There are significantly fewer neutrophils in the oviducts of caspase-11-deficient mice | Mus musculus |
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