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Literature summary for 3.4.22.64 extracted from

  • Wang, S.; Miura, M.; Jung, Y.K.; Zhu, H.; Li, E.; Yuan, J.
    Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE (1998), Cell, 92, 501-509.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus overexpression induces apoptosis ?
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 ?
additional information Mus musculus pro-caspase-11 physically interacts with pro-ICE in cells, the expression of casp-11 is essential for activation of ICE. Caspase-11 is a compinent of ICE complex and is required for the activation of ICE. Important role of ICE and caspase-11 in mediating apoptosis in pathological conditions ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information overexpression induces apoptosis Mus musculus ?
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 ?
additional information pro-caspase-11 physically interacts with pro-ICE in cells, the expression of casp-11 is essential for activation of ICE. Caspase-11 is a compinent of ICE complex and is required for the activation of ICE. Important role of ICE and caspase-11 in mediating apoptosis in pathological conditions Mus musculus ?
-
 ?