Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | caspase-8-cleaved caspase-9 induces lysosomal membrane permeabilization but fails to activate the effector caspases whereas apoptosome-dependent activation of caspase-9 can trigger both events. Caspase-9 plays a dual role in cell death signaling, as an activator of effector caspases and lysosomal membrane permeabilization | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | embryonic | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | caspase-8-cleaved caspase-9 induces lysosomal membrane permeabilization but fails to activate the effector caspases whereas apoptosome-dependent activation of caspase-9 can trigger both events. Caspase-9 plays a dual role in cell death signaling, as an activator of effector caspases and lysosomal membrane permeabilization | Mus musculus | ? | - |
? |