Literature summary for 3.4.22.62 extracted from

Chen, M.; Guerrero, A.D.; Huang, L.; Shabier, Z.; Pan, M.; Tan, T.H.; Wang, J.
Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members (2007), J. Biol. Chem., 282, 33888-33895.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	caspase-9 signaling cascade induces feedback disruption of the mitochondrion during apoptosis through cleavage of anti-apoptotic Bcl-2, Bcl-xL, and Mcl-1	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
JURKAT cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	caspase-9 signaling cascade induces feedback disruption of the mitochondrion during apoptosis through cleavage of anti-apoptotic Bcl-2, Bcl-xL, and Mcl-1	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)