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Literature summary for 3.4.22.62 extracted from
- The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32 (1996), J. Biol. Chem., 271, 27099-27106.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 46200 | - |
x * 46200, calculation from nucleotide sequence | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P55211 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | CPP32 processes pro-Mch6 preferentially at Asp330 to generate two subunits of molecular masses 37000 Da and 10000 Da. Granzyme B can also process pro-Mch6 but at a site N-terminal to that cleaved by CPP32 and generates two cleavage products, a large 35000 Da product and a small 12000 Da product | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| JURKAT cell | - |
Homo sapiens | - |
| T-cell | - |
Homo sapiens | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 46200, calculation from nucleotide sequence | Homo sapiens |
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