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Literature summary for 3.4.22.61 extracted from

  • Sun, S.; Ge, X.; Zhu, J.; Zhang, W.; Zhang, Q.
    Molecular cloning, immunohistochemical localization, characterization and expression analysis of caspase-8 from the blunt snout bream (Megalobrama amblycephala) exposed to ammonia (2015), Fish Shellfish Immunol., 47, 645-654 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Megalobrama amblycephala
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-
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Posttranslational Modification

Posttranslational Modification Comment Organism
additional information predicted as a non-secretory protein without a signal peptide Megalobrama amblycephala

Source Tissue

Source Tissue Comment Organism Textmining
liver caspase-8 transcripts are detected in liver after exposure to ammonia Megalobrama amblycephala
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Subunits

Subunits Comment Organism
? x * 55960, calculated from sequence Megalobrama amblycephala

pI Value

Organism Comment pI Value Maximum pI Value
Megalobrama amblycephala calculated from sequence
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5.9

General Information

General Information Comment Organism
physiological function caspase-8 of fish may play an essential role in ammonia induced apoptosis. Caspase-8 transcripts are detected in liver after exposure to ammonia. Caspase-8 cleaved fragment is detected and significant alteration of procaspase-8 level is found with the same ammonia treatment condition. Remarkable changes of immunopositive staining are observed after ammonia treatment Megalobrama amblycephala