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Literature summary for 3.4.22.61 extracted from

  • Shen, C.; Yue, H.; Pei, J.; Guo, X.; Wang, T.; Quan, J.M.
    Crystal structure of the death effector domains of caspase-8 (2015), Biochem. Biophys. Res. Commun., 463, 297-302 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
structure of the N-terminal tandem death effector domains, DEDs and comparison with caspase 8 of Molluscum contagiosum virus subtype 1 Homo sapiens

Protein Variants

Protein Variants Comment Organism
F122A/I128D mutations in the N-terminal tandem death effector domains. Mutations markedly reduce the aggregation and improve the solubility Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q14790
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