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Literature summary for 3.4.22.61 extracted from

  • Chang, S.H.; Bae, J.H.; Hong, D.P.; Choi, K.D.; Kim, S.C.; Her, E.; Kim, S.H.; Kang, C.D.
    Dryopteris crassirhizoma has anti-cancer effects through both extrinsic and intrinsic apoptotic pathways and G0/G1 phase arrest in human prostate cancer cells (2010), J. Ethnopharmacol., 130, 248-254.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Bid peptide + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
PC3-MM2 cell
-
Homo sapiens
-
prostate cancer cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Bid peptide + H2O
-
Homo sapiens ?
-
?

Expression

Organism Comment Expression
Homo sapiens Dryopteris crassirhizoma extract (0.1 mg/ml for 24-48 h) causes the cleavage of pro-caspase-8 in PC3-MM2 cells, indicating the increased activity of this caspase up