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Literature summary for 3.4.22.61 extracted from

  • Koike, K.; Takaki, A.; Tatsukawa, M.; Suzuki, M.; Shiraha, H.; Iwasaki, Y.; Sakaguchi, K.; Shiratori, Y.
    Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines (2006), Int. J. Oncol., 29, 1253-1261.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-Ile-Glu-Thr-Asp-fluoromethylketone
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Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
HEP-3B cell caspase-8 is the most important factor that controls interferon and 5-fluorouracil-induced apoptosis in hepatoma cell lines Homo sapiens
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Hep-G2 cell caspase-8 is the most important factor that controls interferon and 5-fluorouracil-induced apoptosis in hepatoma cell lines Homo sapiens
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hepatoma HLE cell caspase-8 is the most important factor that controls interferon and 5-fluorouracil-induced apoptosis in hepatoma cell lines Homo sapiens
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Huh-7 cell caspase-8 is the most important factor that controls interferon and 5-fluorouracil-induced apoptosis in hepatoma cell lines Homo sapiens
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PLC/PRF/5 cell caspase-8 is the most important factor that controls interferon and 5-fluorouracil-induced apoptosis in hepatoma cell lines Homo sapiens
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