Literature summary for 3.4.22.61 extracted from

Jenkins, C.E.; Swiatoniowski, A.; Issekutz, A.C.; Lin, T.J.
Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism (2004), J. Biol. Chem., 279, 37201-37207.

Search for more literature for 3.4.22.61

Application

Application	Comment	Organism
medicine	caspase-8 plays an important role in Pseudomonas aeruginosa Exotoxin A-induced mast cell apoptosis	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
benzyloxycarbonyl-IETD-fluoromethyl ketone	-	Homo sapiens
Fas-associated death domain-like interleukin 1-converting enzyme-inhibitory proteins	FLIPs, natural inhibitor	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q14790	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HMC-1 cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
caspase-8	-	Homo sapiens

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Release 2023.1 (January 2023)