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Literature summary for 3.4.22.59 extracted from

  • Garner, E.; Martinon, F.; Tschopp, J.; Beard, P.; Raj, K.
    Cells with defective p53-p21-pRb pathway are susceptible to apoptosis induced by p84N5 via caspase-6 (2007), Cancer Res., 67, 7631-7637.
    View publication on PubMed

Application

Application Comment Organism
molecular biology it is shown that caspase-6 is the major caspase responsible for the death of cells infected with Adeno-associated virus (AAV) infection Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information a flag-tagged dominant-negative caspase-6 point mutant is expressed in Saos-2 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
osteosarcoma cell line Saos-2 and U2OS Homo sapiens
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Synonyms

Synonyms Comment Organism
caspase-6
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Homo sapiens