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Literature summary for 3.4.22.59 extracted from

  • Nyormoi, O.; Wang, Z.; Bar-Eli, M.
    Sequence-based discovery of a synthetic peptide inhibitor of caspase 6 (2003), Apoptosis, 8, 371-376.
    View publication on PubMed
Search for more literature for 3.4.22.59

Activating Compound

Activating Compound Comment Organism Structure
Tumor necrosis factor alpha activates caspase-6 which in turn cleaves transcription factor AP2alpha Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-DRHD-fluoromethylketone
-
 Homo sapiens
benzyloxycarbonyl-VAD-fluoromethylketone
-
 Homo sapiens
benzyloxycarbonyl-VEID-fluoromethylketone
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
transcription factor AP-2alpha + H2O Homo sapiens activates caspase-6 which in turn cleaves transcription factor AP2alpha ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
transcription factor AP-2alpha + H2O activates caspase-6 which in turn cleaves transcription factor AP2alpha Homo sapiens ?
-
 ?