Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.56 extracted from

  • Azuma, H.; Yoshida, Y.; Paul, D.; Shinoda, S.; Tsukube, H.; Nagasaki, T.
    Cytochrome c-binding "proteo-dendrimers" as new types of apoptosis inhibitors working in HeLa cell systems (2009), Org. Biomol. Chem., 7, 1700-1704.
    View publication on PubMed
Search for more literature for 3.4.22.56

Activating Compound

Activating Compound Comment Organism Structure
C2-ketoCer i.e. (2S,4E)-2-acetylamino-3-oxo-4-octadecen-1-ol, a ceramide analogue, activates caspase-3 and induces apoptosis Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Ac-DEVD-7-amido-4-methylcoumarin a caspase-3 inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens caspase-3 is involved in apoptosis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epithelial carcinoma cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-
HL-60 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information caspase-3 is involved in apoptosis Homo sapiens ?
-
 ?